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In larger amounts, GLP-1s can send a signal to the brain that the body is full, helping to reduce appetite

The typical progression moves from 0.25 mg to 0.5 mg (5 units) in week five, then continues upward through 1 mg, 1.7 mg, and potentially to 2.4 mg at the highest maintenance dose

3,4 American Association of Clinical Endocrinology guidelines recommend treatment with GLP-1RA in T2DM patients with coexisting ASCVD, high-risk for ASCVD, heart failure, or chronic kidney disease regardless of their glycemic control due to their organ protective effects

It is essential to consult your GP or prescribing clinician before starting or combining these treatments